CD11c expression in chronic lymphocytic leukemia [letter]

CD11c expression in B-cell chronic lymphocytic leukemia.

Sir, CD79b monoclonal antibody (B29) identifies a Bcell restricted molecule that is part of the mb1/B29 disulphide-linked heterodimer which is non-covalently associated with membrane IgM and IgG to constitute the B-cell antigen receptor complex.1 Both B29 and mb1 are restricted to B-lymphocytes, first appearing on the surface at the pre-B-cell stage and remaining through all stages of B-cell di...

CD5+, CD11C+, trap-positive chronic lymphocytic leukemia/prolymphocytic leukemia.

Expression Profiles of miR-93 and miR-330 in Iranian Patients with Chronic Lymphocytic Leukemia

Background and Aims: Chronic lymphocytic leukemia (CLL) is the most common adult human leukemia. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Research has shown that in CLL, microRNAs can have function as oncogenes or tumor suppressors. Some studies demonstrated that the expression of microRNA-93 (miR-93) and microRNA-330 (miR-330) have been changed in several can...

Expression of miR-485-3p and its Target FOXD3 in Chronic Lymphocytic Leukemia

Background and Aims: Previous investigations have revealed that microRNAs (miRNAs) can function as oncogenes or tumor suppressors in chronic lymphocytic leukemia (CLL) and that the expression of miRNAs, such as miR-485-3p changes in several illnesses. This study was designed to determine the expression level of miR-485-3p and its target FOXD3 in CLL patients and controls to identify if this miR...

Dicer Gene Expression as a Prognostic Factor in Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia in Fars Province

Alterations in the expression of microRNAs (miRNAs) have been proposed to play a role in the pathogenesis of acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL). Dicer is one of the main regulators of miRNA biogenesis, and deregulation of its expression has been indicated as a possible cause of miRNA alterations observed in various cancers. Our aim was to analyze the expre...